In a post-apocalyptic world, a small group of survivors, who call themselves Foragers, plan to rebuild civilization from their headquarters in an empty hospital based in what is left of Philadelphia. But they're soon forced into a face-off war with the Rovers, another gang of survivors whom are a brutal gang of cannibals.

A couple's weekend getaway turns into a nightmare after they are stranded in the woods and discover what they assume to be a dead body. The assumption is wrong and John and his girlfriend Jennifer are infected with a deadly disease that will soon ravage their bodies. With no place to go, and no one to turn to, they are forced to find shelter in a deserted cabin. This is where they'll find safety, but this is also where they'll experience a slow and torturous death. They must come to terms with their inevitable deaths, the temptation to kill others to sustain their own lives, and the consequences of murder. They will cling to one another's love and support, but in the end.... all great love stories end tragically.